_id

683a1632c782e11e38d1b26d

id

10103

complaint

[ "Cancer", "Mass" ]

departments

[ "Oncologic", "Reproductive" ]

description

The Risk of Malignancy Index (RMI) for Ovarian Cancer predicts risk that an adnexal mass is malignant.

diseases

[ "Ovarian Cancer" ]

evidence

formula

RMI = menopausal status x ultrasound score x serum CA-125, U/mL

Where menopausal status and ultrasound score are as follows:

*Postmenopausal status = >1 year of amenorrhea or age ≥50 years if patient is status post hysterectomy.

full_title

Risk of Malignancy Index (RMI) for Ovarian Cancer

information

Interpretation:

*71% sensitive and 92% specific for ovarian cancer.

input_schema

[ { "subheading": "Ultrasound features", "subheading_instructions": "", "type": "subheading" }, { "conditionality": "", "default": 0, "label_en": "Multiloculated cysts", "name": "cyst", "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "type": "toggle" }, { "conditionality": "", "default": 0, "label_en": "Solid areas", "name": "areas", "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "type": "toggle" }, { "conditionality": "", "default": 0, "label_en": "Bilateral lesions", "name": "lesions", "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "type": "toggle" }, { "conditionality": "", "default": 0, "label_en": "Ascites", "name": "ascites", "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "type": "toggle" }, { "conditionality": "", "default": 0, "label_en": "Intra-abdominal metastases", "name": "intra", "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "type": "toggle" }, { "subheading": "Other features", "subheading_instructions": "", "type": "subheading" }, { "conditionality": "", "default": 0, "label_en": "Menopausal status", "name": "meno", "optional": false, "options": [ { "label": "Premenopausal or perimenopausal", "value": 1 }, { "label": "Postmenopausal", "value": 3 } ], "show_points": false, "tips_en": "Postmenopausal status = >1 year of amenorrhea or age ≥50 years if patient is status post hysterectomy", "type": "radio" }, { "conditionality": "", "label_en": "Serum CA-125, U/mL", "name": "ca", "optional": false, "type": "textbox", "unit": "ca125" } ]

instructions

ismed

false

keywords

RMI 1, RMI 3, ovarian cancer index, CA125, menopause, ultrasound score, cyst, lesion, ascites, metastases

measurements

[ { "name": "ca125", "unit": "ca125", "error_min": "0", "error_max": "10000", "warn_min": "0", "warn_max": "100", "conversion": "1", "normal_max_si": "35", "normal_max_us": "35", "normal_min_si": "0", "normal_min_us": "0", "units_si": "U/mL", "units_us": "U/mL" } ]

med_description

Predicts risk that an adnexal mass is malignant.

next_actions

next_advice

Consider further workup in patients with elevated RMI.

next_management

pearls

Requires CA-125 level to calculate, which may not otherwise be obtained.

published

purpose

[ "Diagnosis" ]

reasons

refrences

{ "Clinical Practice Guidelines": [ { "href": "", "text": "" } ], "Manufacturer Website": [ { "href": "", "text": "" } ], "Original/Primary Reference": [ { "href": "https://www.ncbi.nlm.nih.gov/pubmed/2223684", "text": "Jacobs I, Oram D, Fairbanks J, Turner J, Frost C, Grudzinskas JG. A risk of malignancy index incorporating CA 125, ultrasound and menopausal status for the accurate preoperative diagnosis of ovarian cancer. Br J Obstet Gynaecol. 1990;97(10):922-9." } ], "Other References": [ { "href": "", "text": "" } ], "Outcomes": [ { "href": "", "text": "" } ], "Validation": [ { "href": "https://www.ncbi.nlm.nih.gov/pubmed/10074998", "text": "Tingulstad S, Hagen B, Skjeldestad FE, Halvorsen T, Nustad K, Onsrud M. The risk-of-malignancy index to evaluate potential ovarian cancers in local hospitals. Obstetrics & Gynecology. 1999;93(3):448-452." } ] }

related

[ { "calcId": 10517, "short_title_en": "IOTA Simple Rules Risk Assessment", "slug": "international-ovarian-tumor-analysis-iota-simple-rules-risk-assessment" }, { "calcId": 10531, "short_title_en": "Swede Score", "slug": "swede-score" }, { "calcId": 10530, "short_title_en": "RCI", "slug": "reids-colposcopic-index-rci" } ]

search_terms

[ "Ovarian cancer index", "metastases", "CA125", "menopause", "ultrasound score", "lesion", "ascites", "cyst", "CA-125" ]

section

[ "pearlsPitfallsViewed", "nextStepsViewed", "evidenceViewed" ]

seo

{ "keywords_en": "RMI 1, RMI 3, ovarian cancer index, CA125, menopause, ultrasound score, cyst, lesion, ascites, metastases", "meta_description_en": "The Risk of Malignancy Index (RMI) for Ovarian Cancer predicts risk that an adnexal mass is malignant." }

short_description

Ovarian cancer risk for adnexal mass.

short_title

RMI for Ovarian Cancer

slug

risk-malignancy-index-rmi-ovarian-cancer

specialty

[ "Hematology and Oncology", "Radiation Oncology", "Internal Medicine", "Hospitalist Medicine", "Surgery (General)", "OB-Gyn" ]

tags

[]

title

Risk of Malignancy Index (RMI) for Ovarian Cancer

usecase

version_number

versions

[]

cleaned_departments

[ "oncology", "gynecology" ]

cleaned_use

[]

pub

false