_id

683a165ac782e11e38d1b380

id

10539

title

MALT Lymphoma Prognostic Index (MALT-IPI)

full_title

MALT Lymphoma Prognostic Index (MALT-IPI)

short_title

MALT-IPI

med_description

Identifies MALT lymphoma patients at risk of poor outcomes.

short_description

MALT lymphoma prognosis.

slug

malt-lymphoma-prognostic-idex-malt-ipi

description

The MALT Lymphoma Prognostic Index (MALT-IPI) identifies MALT lymphoma patients at risk of poor outcomes.

keywords

MALT Lymphoma Prognostic Index (MALT-IPI), MALT-IPI, MALT Lymphoma Prognostic Index, MALT lymphoma, International Prognostic Index (IPI), IPI, mucosa-associated lymphoid tissue, lymphoma, Ann Arbor Stage, ldh, lymphoma prognosis, lymphoma outcome, event-free survival, EFS, progression-free survival, PFS, cause-specific survival, CSS, overall survival, OS

complaint

[ "Abdominal Distention", "Abdominal Mass", "Abdominal Pain", "Blood in Stool", "Cancer", "Chronic Pain", "Diarrhea", "Excessive Crying", "Fatigue", "Fever", "Heartburn", "Loss of Appetite", "Lymphadenopathy", "Mass", "Rash", "Weakness", "Weight Loss/Gain" ]

formula

The MALT-IPI is calculated by adding the selected points for each variable:

evidence

measurements

[]

information

Interpretation:

refrences

{ "Clinical Practice Guidelines": [], "Manufacturer Website": [], "Original/Primary Reference": [ { "href": "https://pubmed.ncbi.nlm.nih.gov/28720586/", "text": "Thieblemont C, Cascione L, Conconi A, et al. A MALT lymphoma prognostic index. Blood. 2017;130(12):1409-1417." } ], "Other References": [], "Outcomes": [], "Validation": [ { "href": "https://pubmed.ncbi.nlm.nih.gov/30310985/", "text": "Hong J, Cho J, Ko YH, Kim SJ, Kim WS. Validation of the marginal zone lymphoma international prognostic index. Ann Hematol. 2019;98(2):457-464." } ], "Validations": [] }

pearls

• An adaptation of the International Prognostic Index (IPI) that is specific for MALT lymphoma.
• Developed using the patient data set from the International Extranodal Lymphoma Study Group 19 (IELSG-19).
• Factors such as age ≥70 years, elevated serum LDH, and Ann Arbor stage III or IV are associated with greater risks, including greater myelosuppression, increased comorbidities, and poorer outcomes.
• Validated for use in both gastric and non-gastric MALT lymphoma.

usecase

• Utilized in the clinical setting to determine the prognosis of patients with mucosa-associated lymphoid tissue (MALT) lymphoma.
• Can be employed in clinical trials to stratify patients by prognostic risk.

reasons

Identifies patients at an increased risk for disease progression or death, which may aid in tailoring treatment approaches.

next_advice

• Patients classified as low or intermediate risk can often be effectively managed with less aggressive treatments.
• High-risk patients may benefit from earlier or more aggressive treatment.
• The MALT-IPI should be utilized as a supplementary tool rather than the sole basis for treatment decisions. It is necessary to integrate the tool's prognostication with comprehensive clinical judgment and to engage in shared decision-making with patients to tailor individual treatment plans.

next_actions

next_management

diseases

[ "Autoimmune Disorders", "Cancer", "Hematologic Malignancy", "Leukemia/Lymphoma", "Lymphoma" ]

input_schema

[ { "conditionality": null, "default": 0, "label_en": "<p>Age</p>", "md_calc_info_concept": null, "name": "q1", "option_fhir_rules": null, "optional": false, "options": [ { "label": "<70", "value": 0 }, { "label": "≥70", "value": 1 } ], "show_points": true, "tips_en": "", "type": "toggle" }, { "conditionality": null, "default": 0, "label_en": "<p>LDH level</p>", "md_calc_info_concept": null, "name": "q2", "option_fhir_rules": null, "optional": false, "options": [ { "label": "Normal", "value": 0 }, { "label": "Elevated", "value": 1 } ], "show_points": true, "tips_en": "", "type": "toggle" }, { "conditionality": null, "default": 0, "label_en": "<p>Ann Arbor stage</p>", "mdcalc_info_concept": null, "name": "q3", "option_fhir_rules": null, "optional": false, "options": [ { "label": "I or II", "value": 0 }, { "label": "III or IV", "value": 1 } ], "show_points": true, "tips_en": "", "type": "radio" } ]

instructions

published

2024-06-19T18:57:34.496Z

purpose

[ "Prognosis" ]

search_terms

[ "MALT Lymphoma Prognostic Index (MALT-IPI)", "MALT-IPI", "MALT Lymphoma Prognostic Index", "MALT lymphoma", "International Prognostic Index", "IPI", "mucosa-associated lymphoid tissue", "lymphoma", "Ann Arbor Stage", "ldh", "lymphoma prognosis", "lymphoma outcome", "event-free survival", "EFS", "progression-free survival", "PFS", "cause-specific survival", "CSS", "overall survival", "OS" ]

seo

{ "keywords_en": "MALT Lymphoma Prognostic Index (MALT-IPI), MALT-IPI, MALT Lymphoma Prognostic Index, MALT lymphoma, International Prognostic Index (IPI), IPI, mucosa-associated lymphoid tissue, lymphoma, Ann Arbor Stage, ldh, lymphoma prognosis, lymphoma outcome, event-free survival, EFS, progression-free survival, PFS, cause-specific survival, CSS, overall survival, OS", "meta_description_en": "The MALT Lymphoma Prognostic Index (MALT-IPI) identifies MALT lymphoma patients at risk of poor outcomes." }

specialty

[ "Family Practice", "Gastroenterology", "Hematology and Oncology", "Hospitalist Medicine", "Internal Medicine", "Palliative Care/Hospice", "Pathology", "Primary Care", "Radiation Oncology" ]

departments

[ "Dermatologic", "Digestive", "Gastrointestinal", "Hematologic", "Oncologic" ]

tags

[]

version_number

1

versions

[]

related

[ { "calcId": 10490, "short_title_en": "NCCN-IPI", "slug": "national-comprehensive-cancer-network-international-prognostic-index-nccn-ipi" }, { "calcId": 10488, "short_title_en": "CNS-IPI", "slug": "central-nervous-system-international-prognostic-index-cns-ipi" }, { "calcId": 4053, "short_title_en": "MIPI", "slug": "mantle-cell-lymphoma-international-prognostic-index-mipi" } ]

ismed

false

section

[ "whenToUseViewed", "pearlsPitfallsViewed", "whyUseViewed", "nextStepsViewed", "evidenceViewed" ]

cleaned_departments

[ "dermatology", "gastroenterology", "gastroenterology", "hematology", "oncology" ]

cleaned_use

[ "Utilized in the clinical setting to determine the prognosis of patients with mucosa-associated lymphoid tissue (MALT) lymphoma.", "Can be employed in clinical trials to stratify patients by prognostic risk." ]

pub

false