_id

683a1630c782e11e38d1b25e

id

10086

complaint

[ "Abdominal Pain", "Fatigue" ]

departments

[ "Endocrine and Metabolic" ]

description

The BARD Score for NAFLD Fibrosis predicts the risk of advanced fibrosis for NAFLD patients.

diseases

[ "Cirrhosis", "Diabetes Mellitus", "Obesity" ]

evidence

The Bard Score was derived by Harrison et al (2008) in a retrospective study of 827 patients. All the patients had biopsy-proven NAFLD. A score of 2–4 was associated with an OR for advanced fibrosis of 17 (CI 9.2-31.9) and a negative predictive value of 96%. Limitations of the study include retrospective design, lack of population diversity, low sensitivity.

formula

Addition of the selected points:

full_title

BARD Score for NAFLD Fibrosis

information

Interpretation:

BARD Score

Risk of advanced fibrosis

0-1

Low

2-4

High*

*Scores 2-4 were associated with odds ratio (OR) 17 (95% CI 9.2-31.9) and 96% NPV (Harrison 2008).

input_schema

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instructions

ismed

true

keywords

BARD score, NAFLD, fibrosis, advanced fibrosis, bard

measurements

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med_description

Predicts risk of advanced fibrosis in NAFLD patients.

next_actions

Patients with advanced fibrosis can be monitored closely on the basis of BARD score for their disease progression and can be referred to liver transplant centers.

next_advice

Patients identified at high risk of fibrosis related to NAFLD can get focused interventions to prevent future complications through life style modifications.

next_management

Lifestyle modifications include:

  • Tight glycemic control

  • Blood pressure control

  • Balanced diet

  • Regular aerobic exercise

pearls

  • Strong negative predictive value for ruling out fibrosis (Raszeja-Wyszomirska 2010).

  • Original study involved mostly Caucasian patients and therefore score may be less applicable in other populations.

  • Doesn’t predict fibrosis but rules out (high sensitivity).

  • Helps differentiate adult patients with NAFLD from NASH who have not yet developed clinical stigmata of cirrhosis.

published

purpose

[ "Diagnosis" ]

reasons

Predicts advanced fibrosis in NAFLD patients with a NPV of 97% (rules out fibrosis), thus potentially avoiding need for liver biopsy. Comparable to NAFLD Fibrosis Score in terms of sensitivity and specificity.

refrences

{ "Clinical Practice Guidelines": [ { "href": "", "text": "" } ], "Manufacturer Website": [ { "href": "", "text": "" } ], "Original/Primary Reference": [ { "href": "https://www.ncbi.nlm.nih.gov/pubmed/18390575 ", "text": "Harrison SA, Oliver D, Arnold HL, Gogia S, Neuschwander-tetri BA. Development and validation of a simple NAFLD clinical scoring system for identifying patients without advanced disease. Gut. 2008;57(10):1441-7. " } ], "Other References": [ { "href": "", "text": "" } ], "Outcomes": [ { "href": "", "text": "" } ], "Validation": [ { "href": "https://bmcgastroenterol.biomedcentral.com/articles/10.1186/1471-230X-10-67 ", "text": "Raszeja-wyszomirska J, Szymanik B, Ławniczak M, et al. Validation of the BARD scoring system in Polish patients with nonalcoholic fatty liver disease (NAFLD). BMC Gastroenterol. 2010;10:67." }, { "href": "https://www.journal-of-hepatology.eu/article/S0168-8278(10)00718-X/abstract ", "text": "Ruffillo G, Fassio E, Alvarez E, et al. Comparison of NAFLD fibrosis score and BARD score in predicting fibrosis in nonalcoholic fatty liver disease. J Hepatol. 2011;54(1):160-3." }, { "href": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560810/ ", "text": "Cichoż-lach H, Celiński K, Prozorow-król B, Swatek J, Słomka M, Lach T. The BARD score and the NAFLD fibrosis score in the assessment of advanced liver fibrosis in nonalcoholic fatty liver disease. Med Sci Monit. 2012;18(12):CR735-40." } ], "Validations": [] }

related

[ { "calcId": 10508, "short_title_en": "Fibrotic NASH Index (FNI)", "slug": "fibrotic-nash-index-fni" }, { "calcId": 10068, "short_title_en": "NAFLD Activity Score", "slug": "nafld-non-alcoholic-fatty-liver-disease-activity-score" }, { "calcId": 3081, "short_title_en": "NAFLD Fibrosis Score", "slug": "nafld-non-alcoholic-fatty-liver-disease-fibrosis-score" } ]

search_terms

[ "BARD", "fibrosis", "NAFLD", "Bard NAFLD", "Bard score" ]

section

[ "whenToUseViewed", "pearlsPitfallsViewed", "whyUseViewed", "nextStepsViewed", "evidenceViewed" ]

seo

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short_description

short_title

BARD Score

slug

bard-score-nafld-fibrosis

specialty

[ "Critical Care", "Family Practice", "Hepatology", "Hospitalist Medicine", "Internal Medicine", "Primary Care" ]

tags

[]

title

BARD Score for NAFLD Fibrosis

usecase

Patients with suspected NAFLD.

version_number

versions

[]

cleaned_departments

[ "endocrine" ]

cleaned_use

[ "Patients with suspected NAFLD." ]

pub

false

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Diabetes