683a1630c782e11e38d1b25e
10086
[ "Abdominal Pain", "Fatigue" ]
[ "Endocrine and Metabolic" ]
The BARD Score for NAFLD Fibrosis predicts the risk of advanced fibrosis for NAFLD patients.
[ "Cirrhosis", "Diabetes Mellitus", "Obesity" ]
The Bard Score was derived by Harrison et al (2008) in a retrospective study of 827 patients. All the patients had biopsy-proven NAFLD. A score of 2–4 was associated with an OR for advanced fibrosis of 17 (CI 9.2-31.9) and a negative predictive value of 96%. Limitations of the study include retrospective design, lack of population diversity, low sensitivity.
Addition of the selected points:
BARD Score for NAFLD Fibrosis
Interpretation:
|
BARD Score |
Risk of advanced fibrosis |
|
0-1 |
Low |
|
2-4 |
High* |
*Scores 2-4 were associated with odds ratio (OR) 17 (95% CI 9.2-31.9) and 96% NPV (Harrison 2008).
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true
BARD score, NAFLD, fibrosis, advanced fibrosis, bard
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Predicts risk of advanced fibrosis in NAFLD patients.
Patients with advanced fibrosis can be monitored closely on the basis of BARD score for their disease progression and can be referred to liver transplant centers.
Patients identified at high risk of fibrosis related to NAFLD can get focused interventions to prevent future complications through life style modifications.
Lifestyle modifications include:
Tight glycemic control
Blood pressure control
Balanced diet
Regular aerobic exercise
Strong negative predictive value for ruling out fibrosis (Raszeja-Wyszomirska 2010).
Original study involved mostly Caucasian patients and therefore score may be less applicable in other populations.
Doesn’t predict fibrosis but rules out (high sensitivity).
Helps differentiate adult patients with NAFLD from NASH who have not yet developed clinical stigmata of cirrhosis.
[ "Diagnosis" ]
Predicts advanced fibrosis in NAFLD patients with a NPV of 97% (rules out fibrosis), thus potentially avoiding need for liver biopsy. Comparable to NAFLD Fibrosis Score in terms of sensitivity and specificity.
{ "Clinical Practice Guidelines": [ { "href": "", "text": "" } ], "Manufacturer Website": [ { "href": "", "text": "" } ], "Original/Primary Reference": [ { "href": "https://www.ncbi.nlm.nih.gov/pubmed/18390575 ", "text": "Harrison SA, Oliver D, Arnold HL, Gogia S, Neuschwander-tetri BA. Development and validation of a simple NAFLD clinical scoring system for identifying patients without advanced disease. Gut. 2008;57(10):1441-7. " } ], "Other References": [ { "href": "", "text": "" } ], "Outcomes": [ { "href": "", "text": "" } ], "Validation": [ { "href": "https://bmcgastroenterol.biomedcentral.com/articles/10.1186/1471-230X-10-67 ", "text": "Raszeja-wyszomirska J, Szymanik B, Ławniczak M, et al. Validation of the BARD scoring system in Polish patients with nonalcoholic fatty liver disease (NAFLD). BMC Gastroenterol. 2010;10:67." }, { "href": "https://www.journal-of-hepatology.eu/article/S0168-8278(10)00718-X/abstract ", "text": "Ruffillo G, Fassio E, Alvarez E, et al. Comparison of NAFLD fibrosis score and BARD score in predicting fibrosis in nonalcoholic fatty liver disease. J Hepatol. 2011;54(1):160-3." }, { "href": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560810/ ", "text": "Cichoż-lach H, Celiński K, Prozorow-król B, Swatek J, Słomka M, Lach T. The BARD score and the NAFLD fibrosis score in the assessment of advanced liver fibrosis in nonalcoholic fatty liver disease. Med Sci Monit. 2012;18(12):CR735-40." } ], "Validations": [] }
[ { "calcId": 10508, "short_title_en": "Fibrotic NASH Index (FNI)", "slug": "fibrotic-nash-index-fni" }, { "calcId": 10068, "short_title_en": "NAFLD Activity Score", "slug": "nafld-non-alcoholic-fatty-liver-disease-activity-score" }, { "calcId": 3081, "short_title_en": "NAFLD Fibrosis Score", "slug": "nafld-non-alcoholic-fatty-liver-disease-fibrosis-score" } ]
[ "BARD", "fibrosis", "NAFLD", "Bard NAFLD", "Bard score" ]
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BARD Score
bard-score-nafld-fibrosis
[ "Critical Care", "Family Practice", "Hepatology", "Hospitalist Medicine", "Internal Medicine", "Primary Care" ]
[]
BARD Score for NAFLD Fibrosis
Patients with suspected NAFLD.
[]
[ "endocrine" ]
[ "Patients with suspected NAFLD." ]
false