683a15f1c782e11e38d1b0b0
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ASAS Criteria for Axial Spondyloarthritis (SpA)
ASAS Criteria for Axial Spondyloarthritis (SpA)
ASAS Criteria for Axial SpA
Classifies axial spondyloarthritis according to Assessment of Spondyloarthritis International Society (ASAS) criteria.
Axial SpA classification.
asas-criteria-axial-spondyloarthritis-spa
The ASAS Criteria for Axial Spondyloarthritis (SpA) diagnoses axial spondyloarthritis according to Assessment of Spondyloarthritis International Society (ASAS) criteria.
Spondyloarthritis, spa, spondylitis, sacroiliitis, si joint
[ "Pain" ]
Entry criterion:
Back pain ≥3 months and age at onset <45 years
Required criteria:
Sacroiliitis on imaging* plus ≥1 SpA feature, or
HLA-B27 plus ≥2 additional SpA features
SpA features:
*Active (acute) inflammation on MRI highly suggestive of SpA-associated sacroiliitis, or definite radiographic sacroiliitis according to modified New York criteria (bilateral grade 2-4 sacroiliitis or unilateral grade 3-4 sacroiliitis, Van Der Linden 1984).
[]
{ "Clinical Practice Guidelines": [ { "href": "https://www.rheumatology.org/Portals/0/Files/Recommendations%20for%20the%20Treatment%20of%20Ankylosing%20Spondylitis.pdf ", "text": "Ward MM, Deodhar A, Akl EA, et al. American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network 2015 Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis. Arthritis Rheumatol. 2016;68(2):282-98." } ], "Manufacturer Website": [ { "href": "", "text": "" } ], "Original/Primary Reference": [ { "href": "https://ard.bmj.com/content/annrheumdis/68/6/777.full.pdf ", "text": "Rudwaleit M, Van Der Heijde D, Landewé R, et al. The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis. 2009;68(6):777-83." } ], "Other References": [ { "href": "https://www.ncbi.nlm.nih.gov/pubmed/6231933 ", "text": "Van Der Linden S, Valkenburg HA, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum. 1984;27(4):361-8." } ], "Outcomes": [ { "href": "", "text": "" } ], "Validation": [ { "href": "", "text": "" } ], "Validations": [] }
Patients with lower back pain in whom spondyloarthritis is in the differential diagnosis.
Strong recommendations for patients with axial SpA from the American College of Rheumatology (ACR) include:
[ "Rheumatoid Arthritis" ]
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{ "conditionality": null, "default": 0, "label_en": "Back pain ≥3 months and age at onset <45 years", "md_calc_info_concept": null, "name": "backpain", "option_fhir_rules": null, "optional": true, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "", "type": "toggle" }
{ "inct": null, "option_fhir_rules": null, "subheading": "Required criteria, ≥1 in addition to the above, both result in positive classification:", "subheading_instructions": null, "type": "subheading" }
{ "conditionality": "backpain == 1", "default": 0, "label_en": "<p>Sacroiliitis on imaging</p>", "mdcalc_info_concept": null, "name": "sacro", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Sacroiliitis on imaging = active (acute) inflammation on MRI highly suggestive of SpA-associated sacroiliitis, or definite radiographic sacroiliitis according to modified New York criteria", "type": "radio" }
{ "conditionality": "backpain == 1", "default": 0, "label_en": "<p>HLA-B27</p>", "md_calc_info_concept": null, "name": "hla", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "", "type": "toggle" }
{ "inct": null, "option_fhir_rules": null, "subheading": "SpA features, ≥1 required if sacroiliitis on imaging; ≥2 features other than HLA-B27 if HLA-B27 positive:", "subheading_instructions": null, "type": "subheading" }
{ "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Inflammatory back pain</p>", "md_calc_info_concept": null, "name": "ibp", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "At least 4/5 present: (1) age at onset <40 years, (2) insidious onset, (3) improvement with exercise, (4) no improvement with rest, (5) pain at night with improvement upon getting up", "type": "toggle" }
{ "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Arthritis</p>", "md_calc_info_concept": null, "name": "arthritis", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Past or present active synovitis (peripheral) diagnosed by a physician", "type": "toggle" }
{ "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Enthesitis (heel)</p>", "md_calc_info_concept": null, "name": "enthesitis", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Past or present spontaneous pain or tenderness at Achilles insertion or plantar fascia at calcaneus", "type": "toggle" }
{ "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Uveitis</p>", "md_calc_info_concept": null, "name": "uveitis", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Past or present uveitis anterior, confirmed by an ophthalmologist", "type": "toggle" }
{ "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Dactylitis</p>", "md_calc_info_concept": null, "name": "dactylitis", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Past or present, diagnosed by a physician", "type": "toggle" }
{ "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Psoriasis</p>", "md_calc_info_concept": null, "name": "psoriasis", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Past or present, diagnosed by a physician", "type": "toggle" }
{ "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Crohn's disease or ulcerative colitis</p>", "md_calc_info_concept": null, "name": "crohns", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "", "type": "toggle" }
{ "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Good response to NSAIDs</p>", "md_calc_info_concept": null, "name": "nsaids", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Resolution or improvement of back pain 24–48 hrs after full dose of NSAID", "type": "toggle" }
{ "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Family history of SpA</p>", "md_calc_info_concept": null, "name": "famhx", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": " Presence in 1st- or 2nd-degree relatives of any of the following: (1) ankylosing spondylitis, (2) psoriasis, (3) acute uveitis, (4) reactive arthritis, (5) IBD", "type": "toggle" }
{ "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Elevated CRP</p>", "md_calc_info_concept": null, "name": "crp", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "After exclusion of other causes for elevated CRP", "type": "toggle" }
[ { "inct": null, "option_fhir_rules": null, "subheading": "Entry criterion:", "subheading_instructions": "", "type": "subheading" }, { "conditionality": null, "default": 0, "label_en": "Back pain ≥3 months and age at onset <45 years", "md_calc_info_concept": null, "name": "backpain", "option_fhir_rules": null, "optional": true, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "", "type": "toggle" }, { "inct": null, "option_fhir_rules": null, "subheading": "Required criteria, ≥1 in addition to the above, both result in positive classification:", "subheading_instructions": null, "type": "subheading" }, { "conditionality": "backpain == 1", "default": 0, "label_en": "<p>Sacroiliitis on imaging</p>", "mdcalc_info_concept": null, "name": "sacro", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Sacroiliitis on imaging = active (acute) inflammation on MRI highly suggestive of SpA-associated sacroiliitis, or definite radiographic sacroiliitis according to modified New York criteria", "type": "radio" }, { "conditionality": "backpain == 1", "default": 0, "label_en": "<p>HLA-B27</p>", "md_calc_info_concept": null, "name": "hla", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "", "type": "toggle" }, { "inct": null, "option_fhir_rules": null, "subheading": "SpA features, ≥1 required if sacroiliitis on imaging; ≥2 features other than HLA-B27 if HLA-B27 positive:", "subheading_instructions": null, "type": "subheading" }, { "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Inflammatory back pain</p>", "md_calc_info_concept": null, "name": "ibp", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "At least 4/5 present: (1) age at onset <40 years, (2) insidious onset, (3) improvement with exercise, (4) no improvement with rest, (5) pain at night with improvement upon getting up", "type": "toggle" }, { "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Arthritis</p>", "md_calc_info_concept": null, "name": "arthritis", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Past or present active synovitis (peripheral) diagnosed by a physician", "type": "toggle" }, { "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Enthesitis (heel)</p>", "md_calc_info_concept": null, "name": "enthesitis", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Past or present spontaneous pain or tenderness at Achilles insertion or plantar fascia at calcaneus", "type": "toggle" }, { "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Uveitis</p>", "md_calc_info_concept": null, "name": "uveitis", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Past or present uveitis anterior, confirmed by an ophthalmologist", "type": "toggle" }, { "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Dactylitis</p>", "md_calc_info_concept": null, "name": "dactylitis", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Past or present, diagnosed by a physician", "type": "toggle" }, { "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Psoriasis</p>", "md_calc_info_concept": null, "name": "psoriasis", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Past or present, diagnosed by a physician", "type": "toggle" }, { "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Crohn's disease or ulcerative colitis</p>", "md_calc_info_concept": null, "name": "crohns", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "", "type": "toggle" }, { "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Good response to NSAIDs</p>", "md_calc_info_concept": null, "name": "nsaids", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "Resolution or improvement of back pain 24–48 hrs after full dose of NSAID", "type": "toggle" }, { "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Family history of SpA</p>", "md_calc_info_concept": null, "name": "famhx", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": " Presence in 1st- or 2nd-degree relatives of any of the following: (1) ankylosing spondylitis, (2) psoriasis, (3) acute uveitis, (4) reactive arthritis, (5) IBD", "type": "toggle" }, { "conditionality": "backpain == 1 && (sacro == 0 || hla == 0)", "default": 0, "label_en": "<p>Elevated CRP</p>", "md_calc_info_concept": null, "name": "crp", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": false, "tips_en": "After exclusion of other causes for elevated CRP", "type": "toggle" } ]
2022-04-21T20:29:11.999Z
[ "Diagnosis" ]
[ "Spondyloarthritis", "spa", "spondylitis", "sacroiliitis", "Assessment of Spondyloarthritis International Society", "si joint" ]
{ "keywords_en": "Spondyloarthritis, spa, spondylitis, sacroiliitis, si joint", "meta_description_en": "The ASAS Criteria for Axial Spondyloarthritis (SpA) diagnoses axial spondyloarthritis according to Assessment of Spondyloarthritis International Society (ASAS) criteria." }
[ "Rheumatology" ]
[ "Musculoskeletal", "Rheumatologic" ]
[]
1
[]
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false
[ "whenToUseViewed", "nextStepsViewed", "evidenceViewed" ]
[ "orthopedics", "rheumatology" ]
[ "Patients with lower back pain in whom spondyloarthritis is in the differential diagnosis." ]
false