_id

683a161ac782e11e38d1b1cc

id

3984

title

Appendicitis Inflammatory Response (AIR) Score

full_title

Appendicitis Inflammatory Response (AIR) Score

short_title

AIR Score

med_description

Diagnoses appendicitis based on clinical and laboratory findings.

short_description

Diagnoses appendicitis.

slug

appendicitis-inflammatory-response-air-score

description

The Appendicitis Inflammatory Response Score diagnoses appendicitis based on clinical and laboratory findings.

keywords

Air score, alvarado score, acute appendicitis, appy, appendectomy

complaint

[ "Abdominal Pain", "Pain", "Vomiting" ]

formula

Addition of selected points:

evidence

measurements

[]

information

Interpretation:

AIR Score

Risk

Recommendation

0–4

Low

Outpatient follow-up (if unaltered general condition)

5–8

Indeterminate

In-hospital active observation with serial re-exams, imaging, or diagnostic laparoscopy, according to local practice

9–12

High

Surgical exploration

refrences

{ "Clinical Practice Guidelines": [], "Manufacturer Website": [], "Original/Primary Reference": [ { "href": "https://link.springer.com/article/10.1007/s00268-008-9649-y", "text": "Andersson M, Andersson RE. The appendicitis inflammatory response score: a tool for the diagnosis of acute appendicitis that outperforms the Alvarado score. World J Surg. 2008;32(8):1843-9." } ], "Other References": [ { "href": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299622/ ", "text": "Ohle R, O'reilly F, O'brien KK, Fahey T, Dimitrov BD. The Alvarado score for predicting acute appendicitis: a systematic review. BMC Med. 2011;9:139." } ], "Outcomes": [], "Validation": [ { "href": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368113/ ", "text": "De castro SM, Ünlü C, Steller EP, Van wagensveld BA, Vrouenraets BC. Evaluation of the appendicitis inflammatory response score for patients with acute appendicitis. World J Surg. 2012;36(7):1540-5." }, { "href": "https://www.ncbi.nlm.nih.gov/pubmed/28730753", "text": "Andersson M, Kolodziej B, Andersson RE. Randomized clinical trial of Appendicitis Inflammatory Response score-based management of patients with suspected appendicitis. Br J Surg. 2017;104(11):1451-1461." } ], "Validations": [] }

pearls

Requires C-reactive protein value, which is sometimes not part of the routine battery of tests for abdominal pain.

usecase

Use in pediatric or adult patients with suspected appendicitis (large external validation cohort included ages 2-96 years).

reasons

Outperforms the Alvarado Score in a large (n = 941 consecutive patients) external validation cohort (De Castro 2012) with an AUROC of 0.96. May help avoid the need for CT imaging.

next_advice

For patients with an indeterminate AIR Score, clinician judgment should prevail.

next_actions

next_management

diseases

[ "Appendicitis" ]

input_schema

{ "conditionality": "", "default": 0, "label_en": "Vomiting", "md_calc_info_concept": null, "name": "vomit", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": true, "tips_en": "", "type": "toggle" }

{ "conditionality": "", "default": 0, "label_en": "<abbr title='Right iliac fossa'>RIF</abbr> pain", "md_calc_info_concept": null, "name": "pain", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": true, "tips_en": "", "type": "toggle" }

{ "conditionality": "", "default": 0, "label_en": "Rebound tenderness", "mdcalc_info_concept": null, "name": "rebound", "option_fhir_rules": null, "optional": false, "options": [ { "label": "None", "value": 0 }, { "label": "Light", "value": 1 }, { "label": "Medium", "value": 2 }, { "label": "Strong", "value": 3 } ], "show_points": true, "tips_en": "", "type": "radio" }

{ "conditionality": "", "default": 0, "label_en": "Temp ≥101.3ºF (38.5ºC)", "md_calc_info_concept": null, "name": "body", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": true, "tips_en": "", "type": "toggle" }

{ "conditionality": "", "default": 0, "label_en": "Polymorphonuclear leukocytes", "mdcalc_info_concept": null, "name": "poly", "option_fhir_rules": null, "optional": false, "options": [ { "label": "<70%", "value": 0 }, { "label": "70-84%", "value": 1 }, { "label": "≥85%", "value": 2 } ], "show_points": true, "tips_en": "", "type": "radio" }

{ "conditionality": "", "default": 0, "label_en": "WBC count, ×10⁹/L", "mdcalc_info_concept": null, "name": "wbc", "option_fhir_rules": null, "optional": false, "options": [ { "label": "<10", "value": 0 }, { "label": "10.0–14.9", "value": 1 }, { "label": "≥15", "value": 2 } ], "show_points": true, "tips_en": "", "type": "radio" }

{ "conditionality": "", "default": 0, "label_en": "<abbr title='C-reactive protein'>CRP</abbr> level, mg/L", "mdcalc_info_concept": null, "name": "crp", "option_fhir_rules": null, "optional": false, "options": [ { "label": "<10", "value": 0 }, { "label": "10–49", "value": 1 }, { "label": "≥50", "value": 2 } ], "show_points": true, "tips_en": "", "type": "radio" }

[ { "conditionality": "", "default": 0, "label_en": "Vomiting", "md_calc_info_concept": null, "name": "vomit", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": true, "tips_en": "", "type": "toggle" }, { "conditionality": "", "default": 0, "label_en": "<abbr title='Right iliac fossa'>RIF</abbr> pain", "md_calc_info_concept": null, "name": "pain", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": true, "tips_en": "", "type": "toggle" }, { "conditionality": "", "default": 0, "label_en": "Rebound tenderness", "mdcalc_info_concept": null, "name": "rebound", "option_fhir_rules": null, "optional": false, "options": [ { "label": "None", "value": 0 }, { "label": "Light", "value": 1 }, { "label": "Medium", "value": 2 }, { "label": "Strong", "value": 3 } ], "show_points": true, "tips_en": "", "type": "radio" }, { "conditionality": "", "default": 0, "label_en": "Temp ≥101.3ºF (38.5ºC)", "md_calc_info_concept": null, "name": "body", "option_fhir_rules": null, "optional": false, "options": [ { "label": "No", "value": 0 }, { "label": "Yes", "value": 1 } ], "show_points": true, "tips_en": "", "type": "toggle" }, { "conditionality": "", "default": 0, "label_en": "Polymorphonuclear leukocytes", "mdcalc_info_concept": null, "name": "poly", "option_fhir_rules": null, "optional": false, "options": [ { "label": "<70%", "value": 0 }, { "label": "70-84%", "value": 1 }, { "label": "≥85%", "value": 2 } ], "show_points": true, "tips_en": "", "type": "radio" }, { "conditionality": "", "default": 0, "label_en": "WBC count, ×10⁹/L", "mdcalc_info_concept": null, "name": "wbc", "option_fhir_rules": null, "optional": false, "options": [ { "label": "<10", "value": 0 }, { "label": "10.0–14.9", "value": 1 }, { "label": "≥15", "value": 2 } ], "show_points": true, "tips_en": "", "type": "radio" }, { "conditionality": "", "default": 0, "label_en": "<abbr title='C-reactive protein'>CRP</abbr> level, mg/L", "mdcalc_info_concept": null, "name": "crp", "option_fhir_rules": null, "optional": false, "options": [ { "label": "<10", "value": 0 }, { "label": "10–49", "value": 1 }, { "label": "≥50", "value": 2 } ], "show_points": true, "tips_en": "", "type": "radio" } ]

instructions

Use in pediatric or adult patients with suspected appendicitis (large external validation cohort included ages 2-96 years).

published

2022-04-21T20:29:33.008Z

purpose

[ "Diagnosis" ]

search_terms

[ "appendicitis", "appy", "appendectomy", "appendicectomy", "air", "alvarado", "acute appendicitis", "air score" ]

seo

{ "keywords_en": "Air score, alvarado score, acute appendicitis, appy, appendectomy", "meta_description_en": "The Appendicitis Inflammatory Response Score diagnoses appendicitis based on clinical and laboratory findings." }

specialty

[ "Emergency Medicine", "Pediatrics", "Surgery (General)" ]

departments

[ "Gastrointestinal" ]

tags

[]

version_number

1

versions

[]

related

[ { "calcId": 3166, "short_title_en": "RIPASA Score", "slug": "ripasa-score-acute-appendicitis" }, { "calcId": 3926, "short_title_en": "Pediatric Appendicitis Score (PAS)", "slug": "pediatric-appendicitis-score-pas" }, { "calcId": 617, "short_title_en": "Alvarado Score", "slug": "alvarado-score-acute-appendicitis" } ]

ismed

false

section

[ "whenToUseViewed", "pearlsPitfallsViewed", "whyUseViewed", "nextStepsViewed", "evidenceViewed" ]

cleaned_departments

[ "gastroenterology" ]

cleaned_use

[ "Use in pediatric or adult patients with suspected appendicitis (large external validation cohort included ages 2-96 years)." ]

pub

false

Vomiting
<abbr title='Right iliac fossa'>RIF</abbr> pain
Rebound tenderness
Temp ≥101.3ºF (38.5ºC)
Polymorphonuclear leukocytes
WBC count, ×10⁹/L
<abbr title='C-reactive protein'>CRP</abbr> level, mg/L