683a162bc782e11e38d1b23f
10050
[ "Joint Pain", "Pain" ]
[ "Musculoskeletal", "Rheumatologic" ]
The Ankylosing Spondylitis Disease Activity Score with ESR (ASDAS-ESR) describes severity of ankylosing spondylitis (AS) using clinical and laboratory data, specifically ESR.
[ "Rheumatoid Arthritis" ]
ASDAS-ESR = (0.08 x back pain) + (0.07 x duration of morning stiffness) + (0.11 x patient global assessment of disease activity) + (0.09 x Peripheral pain/swelling) + (0.29 x √(ESR)) Where variables are: All variables, except ESR, should be graded on a scale of 0 (least severe) to 10 (most severe).
Ankylosing Spondylitis Disease Activity Score with ESR (ASDAS-ESR)
Interpretation:
|
ASDAS-ESR |
Disease activity |
|
<1.3 |
Inactive |
|
1.3-2.0 |
Low |
|
2.1-3.5 |
High |
|
>3.5 |
Very high |
{ "conditionality": "", "default": 0, "label_en": "Back pain", "name": "backpain", "optional": false, "options": [ { "label": "0: least severe", "value": 0 }, { "label": "1", "value": 1 }, { "label": "2", "value": 2 }, { "label": "3", "value": 3 }, { "label": "4", "value": 4 }, { "label": "5", "value": 5 }, { "label": "6", "value": 6 }, { "label": "7", "value": 7 }, { "label": "8", "value": 8 }, { "label": "9", "value": 9 }, { "label": "10: most severe", "value": 10 } ], "show_points": true, "tips_en": "Ask the patient: \"How would you describe the overall level of AS neck, back, or hip pain you have had?\"", "type": "radio" }
{ "conditionality": "", "default": 0, "label_en": "Duration of morning stiffness", "name": "stiffness", "optional": false, "options": [ { "label": "0: least severe", "value": 0 }, { "label": "1", "value": 1 }, { "label": "2", "value": 2 }, { "label": "3", "value": 3 }, { "label": "4", "value": 4 }, { "label": "5", "value": 5 }, { "label": "6", "value": 6 }, { "label": "7", "value": 7 }, { "label": "8", "value": 8 }, { "label": "9", "value": 9 }, { "label": "10: most severe", "value": 10 } ], "show_points": true, "tips_en": "Ask the patient: \"How would you describe the overall level of morning stiffness you have had from the time you wake up?\"", "type": "radio" }
{ "conditionality": "", "default": 0, "label_en": "Patient global assessment of disease activity", "name": "global", "optional": false, "options": [ { "label": "0: least severe", "value": 0 }, { "label": "1", "value": 1 }, { "label": "2", "value": 2 }, { "label": "3", "value": 3 }, { "label": "4", "value": 4 }, { "label": "5", "value": 5 }, { "label": "6", "value": 6 }, { "label": "7", "value": 7 }, { "label": "8", "value": 8 }, { "label": "9", "value": 9 }, { "label": "10: most severe", "value": 10 } ], "show_points": true, "tips_en": "Ask the patient: \"How active was your spondylitis, on average, during the last week?\"", "type": "radio" }
{ "conditionality": "", "default": 0, "label_en": "Peripheral pain/swelling", "name": "peripheral", "optional": false, "options": [ { "label": "0: least severe", "value": 0 }, { "label": "1", "value": 1 }, { "label": "2", "value": 2 }, { "label": "3", "value": 3 }, { "label": "4", "value": 4 }, { "label": "5", "value": 5 }, { "label": "6", "value": 6 }, { "label": "7", "value": 7 }, { "label": "8", "value": 8 }, { "label": "9", "value": 9 }, { "label": "10: most severe", "value": 10 } ], "show_points": true, "tips_en": "Ask the patient: \"How would you describe the overall level of pain/swelling in joints other than neck, back, or hips you have had?\"", "type": "radio" }
{ "conditionality": "", "label_en": "<abbr title='Erythrocyte sedimentation rate'>ESR</abbr>", "name": "esr", "optional": false, "type": "textbox", "unit": "esr" }
[ { "conditionality": "", "default": 0, "label_en": "Back pain", "name": "backpain", "optional": false, "options": [ { "label": "0: least severe", "value": 0 }, { "label": "1", "value": 1 }, { "label": "2", "value": 2 }, { "label": "3", "value": 3 }, { "label": "4", "value": 4 }, { "label": "5", "value": 5 }, { "label": "6", "value": 6 }, { "label": "7", "value": 7 }, { "label": "8", "value": 8 }, { "label": "9", "value": 9 }, { "label": "10: most severe", "value": 10 } ], "show_points": true, "tips_en": "Ask the patient: \"How would you describe the overall level of AS neck, back, or hip pain you have had?\"", "type": "radio" }, { "conditionality": "", "default": 0, "label_en": "Duration of morning stiffness", "name": "stiffness", "optional": false, "options": [ { "label": "0: least severe", "value": 0 }, { "label": "1", "value": 1 }, { "label": "2", "value": 2 }, { "label": "3", "value": 3 }, { "label": "4", "value": 4 }, { "label": "5", "value": 5 }, { "label": "6", "value": 6 }, { "label": "7", "value": 7 }, { "label": "8", "value": 8 }, { "label": "9", "value": 9 }, { "label": "10: most severe", "value": 10 } ], "show_points": true, "tips_en": "Ask the patient: \"How would you describe the overall level of morning stiffness you have had from the time you wake up?\"", "type": "radio" }, { "conditionality": "", "default": 0, "label_en": "Patient global assessment of disease activity", "name": "global", "optional": false, "options": [ { "label": "0: least severe", "value": 0 }, { "label": "1", "value": 1 }, { "label": "2", "value": 2 }, { "label": "3", "value": 3 }, { "label": "4", "value": 4 }, { "label": "5", "value": 5 }, { "label": "6", "value": 6 }, { "label": "7", "value": 7 }, { "label": "8", "value": 8 }, { "label": "9", "value": 9 }, { "label": "10: most severe", "value": 10 } ], "show_points": true, "tips_en": "Ask the patient: \"How active was your spondylitis, on average, during the last week?\"", "type": "radio" }, { "conditionality": "", "default": 0, "label_en": "Peripheral pain/swelling", "name": "peripheral", "optional": false, "options": [ { "label": "0: least severe", "value": 0 }, { "label": "1", "value": 1 }, { "label": "2", "value": 2 }, { "label": "3", "value": 3 }, { "label": "4", "value": 4 }, { "label": "5", "value": 5 }, { "label": "6", "value": 6 }, { "label": "7", "value": 7 }, { "label": "8", "value": 8 }, { "label": "9", "value": 9 }, { "label": "10: most severe", "value": 10 } ], "show_points": true, "tips_en": "Ask the patient: \"How would you describe the overall level of pain/swelling in joints other than neck, back, or hips you have had?\"", "type": "radio" }, { "conditionality": "", "label_en": "<abbr title='Erythrocyte sedimentation rate'>ESR</abbr>", "name": "esr", "optional": false, "type": "textbox", "unit": "esr" } ]
false
Ankylosing spondylitis, disease activity score, AS, ASDAS, ESR, RA, rheumatoid arthritis, disease activity index, DAS28, DAS28-ESR
[ { "name": "CRP", "unit": "esr", "error_min": "0", "error_max": "100", "warn_min": "0", "warn_max": "50", "conversion": "1", "normal_max_si": "20", "normal_max_us": "20", "normal_min_si": "0", "normal_min_us": "0", "units_si": "mm/hr", "units_us": "mm/hr" } ]
Stratifies severity of ankylosing spondylitis (AS) using clinical and laboratory data, specifically ESR.
May be useful in helping to guide treatment decisions; e.g. detecting improvement with TNF inhibitors.
Other than ESR, all values are self-reported by the patient and therefore subjective.
[ "Diagnosis" ]
The ASDAS-CRP is the preferred disease activity index according to the Assessment of SpondyloArthritis international Society (ASAS), but the ASDAS-ESR may be used as an alternate. May be useful for trending disease activity over time.
{ "Clinical Practice Guidelines": [ { "href": "", "text": "" } ], "Manufacturer Website": [ { "href": "", "text": "" } ], "Original/Primary Reference": [ { "href": "https://www.ncbi.nlm.nih.gov/pubmed/18625618", "text": "Lukas C, Landewé R, Sieper J, et al. Development of an ASAS-endorsed disease activity score (ASDAS) in patients with ankylosing spondylitis. Ann Rheum Dis. 2009;68(1):18-24." } ], "Other References": [ { "href": "https://onlinelibrary.wiley.com/doi/full/10.1002/acr.20575", "text": "Zochling J. Measures of symptoms and disease status in ankylosing spondylitis: Ankylosing Spondylitis Disease Activity Score (ASDAS), Ankylosing Spondylitis Quality of Life Scale (ASQoL), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Global Score (BAS-G), Bath Ankylosing Spondylitis Metrology Index (BASMI), Dougados Functional Index (DFI), and Health Assessment Questionnaire for the Spondylarthropathies (HAQ-S). Arthritis Care Res (Hoboken). 2011;63 Suppl 11:S47-58." } ], "Outcomes": [ { "href": "", "text": "" } ], "Validation": [ { "href": "", "text": "" } ] }
[ { "calcId": 10047, "short_title_en": "ASDAS-CRP for Ankylosing Spondylitis", "slug": "ankylosing-spondylitis-disease-activity-score-crp-asdas-crp" }, { "calcId": 10128, "short_title_en": "Patient Activity Scale II for RA", "slug": "patient-activity-scale-ii-pas-ii-ra" }, { "calcId": 10127, "short_title_en": "Patient Activity Scale for RA", "slug": "patient-activity-scale-pas-ra" } ]
[ "Ankylosing spondylitis", "disease activity score", "AS", "ASDAS", "ESR", "disease activity index" ]
[ "pearlsPitfallsViewed", "whyUseViewed", "nextStepsViewed", "evidenceViewed" ]
{ "keywords_en": "Ankylosing spondylitis, disease activity score, AS, ASDAS, ESR, RA, rheumatoid arthritis, disease activity index, DAS28, DAS28-ESR", "meta_description_en": "The Ankylosing Spondylitis Disease Activity Score with ESR (ASDAS-ESR) describes severity of ankylosing spondylitis (AS) using clinical and laboratory data, specifically ESR." }
ASDAS-ESR for Ankylosing Spondylitis
ankylosing-spondylitis-disease-activity-score-esr-asdas-esr
[ "Rheumatology", "Orthopedics" ]
[]
Ankylosing Spondylitis Disease Activity Score with ESR (ASDAS-ESR)
[]
[ "orthopedics", "rheumatology" ]
[]
false