_id

683a162bc782e11e38d1b23c

id

10047

complaint

[ "Joint Pain", "Pain" ]

departments

[ "Musculoskeletal", "Rheumatologic" ]

description

The Ankylosing Spondylitis Disease Activity Score with CRP (ASDAS-CRP) describes severity of ankylosing spondylitis (AS) using clinical and laboratory data, specifically CRP.

diseases

[ "Rheumatoid Arthritis" ]

evidence

formula

ASDAS-CRP = (0.12 x back pain) + (0.06 x morning stiffness) + (0.11 x patient global assessment of disease activity) + (0.07 x peripheral pain/swelling) + (0.58 x ln(CRP + 1)) Where variables are: All variables, except CRP, should be graded on a scale of 0 (least severe) to 10 (most severe).

full_title

Ankylosing Spondylitis Disease Activity Score with CRP (ASDAS-CRP)

information

Interpretation:

input_schema

[ { "conditionality": "", "default": 0, "label_en": "Back pain", "name": "back", "optional": false, "options": [ { "label": "0: least severe", "value": 0 }, { "label": "1", "value": 1 }, { "label": "2", "value": 2 }, { "label": "3", "value": 3 }, { "label": "4", "value": 4 }, { "label": "5", "value": 5 }, { "label": "6", "value": 6 }, { "label": "7", "value": 7 }, { "label": "8", "value": 8 }, { "label": "9", "value": 9 }, { "label": "10: most severe", "value": 10 } ], "show_points": true, "tips_en": "Ask the patient: \"How would you describe the overall level of AS neck, back, or hip pain you have had?\"", "type": "radio" }, { "conditionality": "", "default": 0, "label_en": "Duration of morning stiffness", "name": "duration", "optional": false, "options": [ { "label": "0: least severe", "value": 0 }, { "label": "1", "value": 1 }, { "label": "2", "value": 2 }, { "label": "3", "value": 3 }, { "label": "4", "value": 4 }, { "label": "5", "value": 5 }, { "label": "6", "value": 6 }, { "label": "7", "value": 7 }, { "label": "8", "value": 8 }, { "label": "9", "value": 9 }, { "label": "10: most severe", "value": 10 } ], "show_points": true, "tips_en": "Ask the patient: \"How would you describe the overall level of morning stiffness you have had from the time you wake up?\"", "type": "radio" }, { "conditionality": "", "default": 0, "label_en": "Patient global assessment of disease activity", "name": "global", "optional": false, "options": [ { "label": "0: least severe", "value": 0 }, { "label": "1", "value": 1 }, { "label": "2", "value": 2 }, { "label": "3", "value": 3 }, { "label": "4", "value": 4 }, { "label": "5", "value": 5 }, { "label": "6", "value": 6 }, { "label": "7", "value": 7 }, { "label": "8", "value": 8 }, { "label": "9", "value": 9 }, { "label": "10: most severe", "value": 10 } ], "show_points": true, "tips_en": "Ask the patient: \"How active was your spondylitis, on average, during the last week?\"", "type": "radio" }, { "conditionality": "", "default": 0, "label_en": "Peripheral pain/swelling", "name": "peripheral", "optional": false, "options": [ { "label": "0: least severe", "value": 0 }, { "label": "1", "value": 1 }, { "label": "2", "value": 2 }, { "label": "3", "value": 3 }, { "label": "4", "value": 4 }, { "label": "5", "value": 5 }, { "label": "6", "value": 6 }, { "label": "7", "value": 7 }, { "label": "8", "value": 8 }, { "label": "9", "value": 9 }, { "label": "10: most severe", "value": 10 } ], "show_points": true, "tips_en": "Ask the patient: \"How would you describe the overall level of pain/swelling in joints other than neck, back, or hips you have had?\"", "type": "radio" }, { "conditionality": "", "label_en": "<abbr title='C-reactive protein'>CRP</abbr>", "name": "crp", "optional": false, "type": "textbox", "unit": "crp_dl" } ]

instructions

ismed

false

keywords

Ankylosing spondylitis, disease activity score, AS, ASDAS, CRP, RA, rheumatoid arthritis, disease activity index, DAS28, DAS28-CRP

measurements

[ { "name": "crp_dl", "unit": "crp_dl", "error_min": "0", "error_max": "200", "warn_min": "0", "warn_max": "100", "conversion": "0.1", "normal_max_si": "0.3", "normal_max_us": "3", "normal_min_si": "0", "normal_min_us": "0", "units_si": "mg/dL", "units_us": "mg/L" } ]

med_description

Stratifies severity of ankylosing spondylitis (AS) using clinical and laboratory data, specifically CRP.

next_actions

next_advice

May be useful in helping to guide treatment decisions; e.g. detecting improvement with TNF inhibitors.

next_management

pearls

Other than CRP, all values are self-reported by the patient and therefore subjective.

published

purpose

[ "Diagnosis" ]

reasons

The ASDAS-CRP is the preferred disease activity index according to the Assessment of SpondyloArthritis international Society (ASAS). May be useful for trending disease activity over time.

refrences

{ "Clinical Practice Guidelines": [ { "href": "", "text": "" } ], "Manufacturer Website": [ { "href": "", "text": "" } ], "Original/Primary Reference": [ { "href": "https://www.ncbi.nlm.nih.gov/pubmed/18625618", "text": "Lukas C, Landewé R, Sieper J, et al. Development of an ASAS-endorsed disease activity score (ASDAS) in patients with ankylosing spondylitis. Ann Rheum Dis. 2009;68(1):18-24." } ], "Other References": [ { "href": "https://onlinelibrary.wiley.com/doi/full/10.1002/acr.20575", "text": "Zochling J. Measures of symptoms and disease status in ankylosing spondylitis: Ankylosing Spondylitis Disease Activity Score (ASDAS), Ankylosing Spondylitis Quality of Life Scale (ASQoL), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Global Score (BAS-G), Bath Ankylosing Spondylitis Metrology Index (BASMI), Dougados Functional Index (DFI), and Health Assessment Questionnaire for the Spondylarthropathies (HAQ-S). Arthritis Care Res (Hoboken). 2011;63 Suppl 11:S47-58." } ], "Outcomes": [ { "href": "", "text": "" } ], "Validation": [ { "href": "", "text": "" } ] }

related

[ { "calcId": 10050, "short_title_en": "ASDAS-ESR for Ankylosing Spondylitis", "slug": "ankylosing-spondylitis-disease-activity-score-esr-asdas-esr" }, { "calcId": 10127, "short_title_en": "Patient Activity Scale for RA", "slug": "patient-activity-scale-pas-ra" }, { "calcId": 10128, "short_title_en": "Patient Activity Scale II for RA", "slug": "patient-activity-scale-ii-pas-ii-ra" } ]

search_terms

[ "Ankylosing spondylitis", "disease activity score", "AS", "ASDAS", "CRP", "disease activity index" ]

section

[ "pearlsPitfallsViewed", "whyUseViewed", "nextStepsViewed", "evidenceViewed" ]

seo

{ "keywords_en": "Ankylosing spondylitis, disease activity score, AS, ASDAS, CRP, RA, rheumatoid arthritis, disease activity index, DAS28, DAS28-CRP", "meta_description_en": "The Ankylosing Spondylitis Disease Activity Score with CRP (ASDAS-CRP) describes severity of ankylosing spondylitis (AS) using clinical and laboratory data, specifically CRP." }

short_description

short_title

ASDAS-CRP for Ankylosing Spondylitis

slug

ankylosing-spondylitis-disease-activity-score-crp-asdas-crp

specialty

[ "Rheumatology", "Orthopedics" ]

tags

[]

title

Ankylosing Spondylitis Disease Activity Score with CRP (ASDAS-CRP)

usecase

version_number

versions

[]

cleaned_departments

[ "orthopedics", "rheumatology" ]

cleaned_use

[]

pub

false