_id

683a1634c782e11e38d1b279

id

10136

complaint

[ "Intoxication/Overdose", "Abdominal Pain" ]

departments

[ "Hepatic" ]

description

The ABIC Score for Alcoholic Hepatitis predicts survival in alcoholic hepatitis.

diseases

[ "Alcoholism", "Drug/Alcohol Use", "Hepatitis" ]

evidence

formula

ABIC Score = (Age, years × 0.1) + (SerumBilirubin, mg/dL × 0.08) + (INR × 0.8) + (SerumCreatinine, mg/dL × 0.3)

full_title

ABIC Score for Alcoholic Hepatitis

information

Interpretation:

ABIC Score

Risk group

Survival at 90 days

Survival at 1 year

<6.71

Low

100%

97.1%

6.71 to <9.00

Intermediate

70%

64.3%

≥9.00

High

25%

33.3%


input_schema

{ "conditionality": "", "label_en": "Age", "name": "age", "optional": false, "type": "textbox", "unit": "age" }

{ "conditionality": "", "label_en": "Serum bilirubin", "name": "bili", "optional": false, "type": "textbox", "unit": "bili" }

{ "conditionality": "", "label_en": "<abbr title = \"International normalized ratio\">INR</abbr>", "name": "inr", "optional": false, "type": "textbox", "unit": "inr" }

{ "conditionality": "", "label_en": "Serum creatinine", "name": "cr", "optional": false, "type": "textbox", "unit": "cr" }

[ { "conditionality": "", "label_en": "Age", "name": "age", "optional": false, "type": "textbox", "unit": "age" }, { "conditionality": "", "label_en": "Serum bilirubin", "name": "bili", "optional": false, "type": "textbox", "unit": "bili" }, { "conditionality": "", "label_en": "<abbr title = \"International normalized ratio\">INR</abbr>", "name": "inr", "optional": false, "type": "textbox", "unit": "inr" }, { "conditionality": "", "label_en": "Serum creatinine", "name": "cr", "optional": false, "type": "textbox", "unit": "cr" } ]

instructions

ismed

false

keywords

Alcohol hepatitis, Alcoholic hepatitis score, Glasgow, Lillie model

measurements

[ { "name": "Age", "unit": "age", "error_min": "0.001", "error_max": "120", "warn_min": "0.1", "warn_max": "100", "conversion": "1", "normal_max_si": "0", "normal_max_us": "0", "normal_min_si": "0", "normal_min_us": "0", "units_si": "years", "units_us": "years" }, { "name": "Creatinine", "unit": "cr", "error_min": "0.01", "error_max": "40", "warn_min": "0", "warn_max": "10", "conversion": "88.4", "normal_max_si": "115", "normal_max_us": "1.3", "normal_min_si": "62", "normal_min_us": "0.7", "units_si": "µmol/L", "units_us": "mg/dL" }, { "name": "Bilirubin", "unit": "bili", "error_min": "1E-8", "error_max": "50", "warn_min": "0", "warn_max": "20", "conversion": "17.104", "normal_max_si": "32.49", "normal_max_us": "1.9", "normal_min_si": "5.13", "normal_min_us": "0.3", "units_si": "µmol/L", "units_us": "mg/dL" }, { "name": "INR", "unit": "inr", "error_min": "0.1", "error_max": "20", "warn_min": "0.5", "warn_max": "10", "conversion": "1", "normal_max_si": "1.2", "normal_max_us": "1.2", "normal_min_si": "0.8", "normal_min_us": "0.8", "units_si": " ", "units_us": " " } ]

med_description

Predicts survival in alcoholic hepatitis.

next_actions

next_advice

We are not aware of any guidelines that recommend steroid administration based on ABIC Score, but could be reasonable to consider in the decision given its mortality prediction by severity.

next_management

pearls

published

purpose

[ "Prognosis" ]

reasons

Performs similarly toMaddrey's Discriminant Functionat predicting mortality, and better than theMELD ScoreandLille Model, in one retrospective study (Garcia-Saenz-de-Sicilia 2017).

refrences

{ "Clinical Practice Guidelines": [ { "href": "", "text": "" } ], "Manufacturer Website": [ { "href": "", "text": "" } ], "Original/Primary Reference": [ { "href": "https://www.ncbi.nlm.nih.gov/pubmed/18721242", "text": "Dominguez M, Rincón D, Abraldes JG, et al. A new scoring system for prognostic stratification of patients with alcoholic hepatitis. Am J Gastroenterol. 2008;103(11):2747-56." } ], "Other References": [ { "href": "", "text": "" } ], "Outcomes": [ { "href": "", "text": "" } ], "Validation": [ { "href": "https://onlinelibrary.wiley.com/doi/full/10.1111/apt.12654", "text": "Papastergiou V, Tsochatzis EA, Pieri G, et al. Nine scoring models for short-term mortality in alcoholic hepatitis: cross-validation in a biopsy-proven cohort. Aliment Pharmacol Ther. 2014;39(7):721-32." }, { "href": "https://www.ncbi.nlm.nih.gov/pubmed/27922027", "text": "Garcia-saenz-de-sicilia M, Duvoor C, Altamirano J, et al. A Day-4 Lille Model Predicts Response to Corticosteroids and Mortality in Severe Alcoholic Hepatitis. Am J Gastroenterol. 2017;112(2):306-315." }, { "href": "https://www.ncbi.nlm.nih.gov/pubmed/23879668", "text": "Lafferty H, Stanley AJ, Forrest EH. The management of alcoholic hepatitis: a prospective comparison of scoring systems. Aliment Pharmacol Ther. 2013;38(6):603-10." } ] }

related

[ { "calcId": 2024, "short_title_en": "Lille Model", "slug": "lille-model-alcoholic-hepatitis" }, { "calcId": 78, "short_title_en": "MELD Na (UNOS/OPTN)", "slug": "meld-score-model-end-stage-liver-disease-12-older" }, { "calcId": 56, "short_title_en": "Maddrey's Discriminant Function", "slug": "maddreys-discriminant-function-alcoholic-hepatitis" } ]

search_terms

[ "Alcohol hepatitis", "Alcoholic hepatitis score" ]

section

[ "whenToUseViewed", "whyUseViewed", "nextStepsViewed", "evidenceViewed" ]

seo

{ "keywords_en": "Alcohol hepatitis, Alcoholic hepatitis score, Glasgow, Lillie model", "meta_description_en": "The ABIC Score for Alcoholic Hepatitis predicts survival in alcoholic hepatitis." }

short_description

short_title

ABIC Score for Alcoholic Hepatitis

slug

abic-score-alcoholic-hepatitis

specialty

[ "Hepatology", "Toxicology", "Gastroenterology" ]

tags

[]

title

ABIC Score for Alcoholic Hepatitis

usecase

Patients with alcoholic hepatitis.

version_number

versions

[]

cleaned_departments

[ "gastroenterology" ]

cleaned_use

[ "Patients with alcoholic hepatitis." ]

pub

false

Age
Serum bilirubin
<abbr title = "International normalized ratio">INR</abbr>
Serum creatinine